Cristiano Ronaldo will be aiming for another record as the Champions League's all-time leading scorer when Real Madrid host a Liverpool side short on confidence at the Santiago Bernabeu on Tuesday.
Ronaldo's opener in the European champions' 3-0 win at Anfield two weeks ago took him to within one goal of Madrid legend Raul's 71 Champions League goals.
A 12th consecutive victory in all competitions would allow Real to seal their place in the last 16 with two games to spare in Group B.
Liverpool are tied with Swiss champions Basel and Champions League debutants Ludogorets Razgrad in a battle for second place on three points.
However, despite suffering a sixth defeat of the season at Newcastle United on Saturday, Liverpool boss Brendan Rodgers insisted his side won't be overawed by the task in front of them.
"We've worked very hard over a couple of years to get to this level," he said.
"To play Real Madrid at the Bernabeu tells us that we've been doing okay. But, of course, we're in a transition phase. We want to be better and we need to be better. So the game Tuesday night is a wonderful game for us. We're still very much in the group to qualify, which is the objective. It's a big ask playing against arguably the best team in the world at the moment. But we'll go into it with confidence. The players will be back up again after Saturday's result and we'll go into that game looking to get something from it".
By contrast, Madrid moved to the top of La Liga for the first time this season with a 4-0 thrashing of Granada on Saturday, taking their goal tally in their 11-game winning streak to 46.