Mourinho's side lead the table by five points after winning six of their first seven matches and are widely expected to cement that position when they travel to Selhurst Park this weekend.
But Blues boss Mourinho remembers only too well that Palace dealt a major blow to Chelsea's title challenge with a shock 1-0 victory in the corresponding fixture last season.
That loss in March prompted Mourinho to concede Chelsea wouldn't win the title and his team eventually finished in third place.
"It was one of those games where I lost and I deserve to lose," Mourinho said.
"I know why I lost. I accept that. Last season we lost there because they were better than us, in every aspect of the game."
Chelsea lacked "balls" on that occasion, Mourinho said at the time, but he is confident they can exert their own influence more decisively this time.