The 2015 Nobel Prize in Chemistry has been awarded for discoveries in DNA repair.
Tomas Lindahl and Paul Modrich and Aziz Sancar were named as the winners on Wednesday morning at a news conference in Stockholm, Sweden.
Their work uncovered the mechanisms used by cells to repair damaged DNA - a fundamental process in living cells.
The prize money of eight million Swedish kronor (£634,000; $970,000) will be shared among the winners.
"It was a surprise. I know that over the years I've occasionally been considered for a prize, but so have hundreds of other people. I feel lucky and proud to be selected today," Tomas Lindahl, from the Francis Crick Institute in the UK, told journalists.
Claes Gustafsson, from the Nobel Committee, said the recipients had "explained the processes at the molecular level that guard the integrity of our genomes".